The diarrhea associated with enterotoxigenic Escherichia coli (ETEC) is the result of:

The diarrhea associated with enterotoxigenic Escherichia coli (ETEC) is the result of:



A. Plasmid-mediated invasion and destruction of epithelial cells lining colon
B. Mediated by cytotoxic Shiga toxins (STx-1, STx-2), which disrupt protein synthesis
C. Plasmid-mediated, heat-stable and/or heat-labile enterotoxins that stimulate hypersecretion of fluids and electrolytes
D. Plasmid-mediated A/E histopathology with disruption of normal microvillus structure resulting in malabsorption and diarrhea


Answer: C. Plasmid-mediated, heat-stable and/or heat-labile enterotoxins that stimulate hypersecretion of fluids and electrolytes


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