The diarrhea associated with enteropathogenic Escherichia coli (EPEC) is the result of:

The diarrhea associated with enteropathogenic Escherichia coli (EPEC) is the result of:



A. Plasmid-mediated A/E histopathology with disruption of normal microvillus structure resulting in malabsorption and diarrhea
B. Plasmid-mediated invasion and destruction of epithelial cells lining colon
C. Mediated by cytotoxic Shiga toxins (STx-1, STx-2), which disrupt protein synthesis
D. Plasmid-mediated, heat-stable and/or heat-labile enterotoxins that stimulate hypersecretion of fluids and electrolytes


Answer: A. Plasmid-mediated A/E histopathology with disruption of normal microvillus structure resulting in malabsorption and diarrhea


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