A 42-year-old patient undergoing treatment with a broad-spectrum antibiotic for several weeks develops profuse, foul-smelling and bloody diarrhea. The patient has fever and abdominal pain. Leukocytes are present in the stool. Cessation of the antibiotic treatment was helpful. Which of the following is the most probable agent of this disease?
A. Shigella
B. Vibrio cholerae
C. Salmonella
D. Escherichia coli
E. Clostridium difficile
Answer: E. Clostridium difficile
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