The secondary signal needed for TH0 helper cells to differentiate into either TH1 cells or TH2 cells is the crosslink between:
a. CD154 (on TH0 helper cells) and CD40 (on APC cell)
b. MHC I (on TH0 helper cells) and B7 (on APC cell)
c. CD4 (on TH0 helper cells) and MHC II (on APC cell)
d. CD8 (on TH0 helper cells) and MHC I (on APC cell)
e. CD28 (on TH0 helper cells) and B7 (on APC cell)
Answer: CD28 (on TH0 helper cells) and B7 (on APC cell)
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