A) Antimicrobial therapy for hemodialysis-associated infections increases antibiotic resistance.
B) S. aureus is differentiated from other mannitol+ cocci by the coagulase test.
C) The M in MRSA stands for mannitol.
D) The USA100 strain accounts for most hospital-acquired MRSA.
E) The USA300 strain accounts for most community-acquired MRSA.
Which of the following is NOT an example of microbial antagonism?
A) acid production by bacteria
B) bacteriocin production
C) bacteria occupying host receptors
D) bacteria causing disease
E) bacteria producing vitamin K
Which of the following can contribute to postoperative infections?
A) using syringes more than once
B) normal microbiota on the operating room staff
C) errors in aseptic technique
D) antibiotic resistance
E) All of the answers are correct.
Emergence of infectious diseases can be attributed to all of the following EXCEPT
A) antibiotic resistance.
B) climatic changes.
C) new strains of previously known agents.
D) ease of travel.
E) None of the answers is correct; the emergence of infectious diseases can be attributed to all of these.
Symptoms of disease differ from signs of disease in that symptoms
A) are changes felt by the patient.
B) are changes observed by the physician.
C) are specific for a particular disease.
D) always occur as part of a syndrome.
E) None of the answers is correct.
A) acute: a short-lasting primary infection
B) inapparent: infection characteristic of a carrier state
C) chronic: a disease that develops slowly and lasts for months
D) primary infection: an initial illness
E) secondary infection: a long-lasting illness
Which of the following statements about biological transmission is FALSE?
A) The pathogen reproduces in the vector.
B) The pathogen may enter the host in the vector's feces.
C) Houseflies are an important vector.
D) The pathogen may be injected by the bite of the vector.
E) The pathogen may require the vector as a host.
One effect of washing regularly with antibacterial agents is the removal of normal microbiota. This can result in
A) body odor.
B) fewer diseases.
C) increased susceptibility to disease.
D) normal microbiota returning immediately.
E) no bacterial growth because washing removes their food source.
Which of the following statements about nosocomial infections is FALSE?
A) They occur in compromised patients.
B) They may be caused by opportunists.
C) They may be caused by drug-resistant bacteria.
D) They may be caused by normal microbiota.
E) The patient was infected before hospitalization.
Transient microbiota differ from normal microbiota in that transient microbiota
A) cause diseases.
B) are found in a certain location on the host.
C) are always acquired by direct contact.
D) are present for a relatively short time.
E) never cause disease.
A) endemic: a disease that is constantly present in a population
B) epidemic: a disease that is endemic across the world
C) pandemic: a disease that affects a large number of people in the world in a short time
D) sporadic: a disease that affects a population occasionally
E) incidence: number of new cases of a disease
Which of the following is NOT a verified exception in the use of Koch's postulates?
A) Some diseases have poorly defined etiologies.
B) Some pathogens can cause several disease conditions.
C) Some human diseases have no other known animal host.
D) Some diseases are not caused by microbes.
E) Some diseases are noncommunicable.
The major significance of Robert Koch's work is that
A) microorganisms are present in a diseased animal.
B) diseases can be transmitted from one animal to another.
C) microorganisms can be cultured.
D) microorganisms cause disease.
E) microorganisms are the result of disease.
A) always present, but is inapparent at the time of hospitalization.
B) acquired during the course of hospitalization.
C) always caused by medical personnel.
D) only a result of surgery.
E) always caused by pathogenic bacteria.
A) At least one member must not benefit in a symbiotic relationship.
B) Members of a symbiotic relationship cannot live without each other.
C) A parasite is not in symbiosis with its host.
D) Symbiosis refers to different organisms living together and benefiting from each other.
E) At least one member must benefit in a symbiotic relationship.
A) does not receive any benefit from its host.
B) is beneficial to its host.
C) may also be an opportunistic pathogen.
D) does not infect its host.
E) is beneficial to, and does not infect, its host.
A sample from an abscess is stained and examined under the microscope. A Gram stain appears uniformly pink, but a GMS (Gomori methenamine sliver) stain reveals brownish filaments in the sample. These findings suggest
a) sporotrichosis
b) necrotizing fasciitis
c) dermatophytosis
d) leishmaniasis
e) phaeohyphomycosis
A child has a rash on the face, arms, upper legs and torso that is splotchy, and intensifies after being in the sun. The child does not complain of fever or itchiness. The signs and symptoms are consistent with
a) cat scratch disease
b) fifth disease
c) roseola
d) chickenpox
e) scabies
A small puncture wound on a woman's arm has become swollen, hot to the touch, and intensely painful. There is tissue necrosis, but it is not "gassy," and under the microscope Gram-positive cocci in chains are present. Which of the following microbes is likely to be responsible?
a) Clostridium perfringens
b) Pseudomonas aeruginosa
c) Streptococcus pyogenes
d) Staphylococcus aureus
e) Sporothrix schenckii
Which of the following forms of leishmaniasis is typically fatal?
a) mucocutaneous
b) cutaneous
c) visceral
d) both cutaneous and mucocutaneous are frequently fatal
e) visceral, mucocutaneous, and cutaneous are all potentially fatal
A child complains of intensely itchy "pimples" on the hands and wrists. The lesions are small inflamed streaks, but do not appear to contain pus. The child's condition may be the result of infection with
a) Staphylococcus epidermidis
b) Pseudomonas aeruginosa
c) Sarcoptes scabiei
d) Sporothrix schenkii
e) Clostridium perfringens
A man is suffering severe foot pain in the area of what looks like a large wart. He reports he has had the wart for some time, and the pain and swelling have developed slowly. A sample from the lesion shows that the pus contains large cells that stain a golden brown color. The man is likely suffering from
a) sporotrichosis
b) phaeohyphomycosis
c) mycetoma
d) chromblasomyosis
e) necrotizing fasciitis
a) parasitic worms that infect the skin
b) immunosuppression due to HIV infection
c) a hypersensitivity reaction caused by superficial contact with dermatophytes
d) dermatophytes that have invaded deep layers of the skin
e) dermatophytes growing in upper dead tissue layers of the skin
Some strains of Papillomavirus are oncogenic due to their ability to
a) produce deoxyribonucleases
b) integrate into the host cell DNA
c) escape the phagosome before lysosome fusion
d) lie dormant in cells for years
e) cause extensive damage to blood vessels
a) analyzed and studied on the genetic level
b) identified as a viral disease
c) treated with antiviral drugs
d) globally eradicated
e) re-created in an experimental animal
What is the pathogenic process underlying Rocky Mountain spotted fever?
a) interference with host cell metabolism
b) stimulation of a strong immune response
c) damage to blood vessels
d) formation of biofilms in host tissues
e) cellular damage via potent exotoxins
a) a pathogen infects the ovaries of its host
b) a pathogen is transmitted through the ingestion of contaminated eggs
c) an infected female vector transmits a pathogen to the eggs in its ovaries
d) a pathogen is spread from host to host by unprotected sexual intercourse
e) a pathogen is transmitted from an infected male to a healthy female during mating
The resistance of Pseudomonas to a wide variety of antimicrobial drugs is due, in part, to its
a) production of exoenzyme S.
b) production of pyocyanin
c) ability to utilize a wide range of carbon and nitrogen sources
d) ability to pump drugs out of the cell
e) ability to grow in almost any moist environment
Anthrax derives its name from which of the following aspects of the disease?
a) the appearance of eschars on the skin
b) the necessity of burning animals killed by the disease
c) the shape of B. anthracis colonies on agar
d) the microscopic appearance of its cells
e) the shape of its endospores
a) Pseudomonas aeruginosa
b) Staphylococcus aureus
c) Rickettsia rickettsii
d) Streptococcus pyogenes
e) both Streptococcus pyogenes ans Staphylococcus aureus
a) Staphylococcus epidermidis
b) Streptococcus pyogenes
c) Staphylococcus aureus
d) both Staphylococcus aureus and Streptococcus pyogenes
e) both Staphylococcus epidermidis and Streptococcus pyogenes
One feature that differentiates Staphylococcus aureus from other staphylococci is its
a) beta-lactamase production
b) slime layer production
c) coagulase production
d) production of both a slime layer and coagulase
e) production of both coagulase and beta-lactamase
The skin is an effective barrier against invading microbes because
a) the outer layers are dead and covered in salt.
b) no microbes are able to survive on the surface.
c) it is well supplied with blood vessels to flush microbes from the surface.
d) the surface is covered in salt.
e) the outer layers of cells are dead